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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay15130-1 | 1 each | - |
6 - 10 business days* |
456.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
GPR120 is a G protein-coupled receptor (GPCR) expressed in adipocytes and pro-inflammatory... more
Product information "Anti-FFAR4 (GPR120) (N-Term)"
GPR120 is a G protein-coupled receptor (GPCR) expressed in adipocytes and pro-inflammatory macrophages that is activated by long chain free fatty acids. The activation of GPR120 results in elevated calcium ion and activation of the ERK cascade. omega-3 Fatty acids, such as docosahexaenoic acid and eicosapentaenoic acid initiate GPR120 signaling resulting in inhibition of toll-like receptor and TNF-alpha inflammatory signaling pathways in a beta-arrestin2/TAB1 dependent manner. The anti-inflammatory effects of GPR120 are indirectly involved with promoting insulin secretion. GPR120 also mediates free fatty acid induced apoptosis inhibition in the enteroendocrin cell line STC-1. Cayman's N-terminal polyclonal antibody detects GPR120 in LoVo and PC3 cell lysates. The predicted size for GPR120 is 42.2 kDa and the observed size is approximately 45 kDa by western blot.Synonyms: Free Fatty Acid Receptor 4, GPCR129, G Protein-Coupled Receptor 120, GT01, O3FAR1, PGR4. Immunogen: Synthetic peptide from the N-terminal region of human FFAR4 (GPR120). Formulation: (Request formulation change), 500 µl of peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: ELISA and WB. UniProt Accession #: Q5NUL3.
Keywords: | Anti-Free fatty acid receptor 4, Anti-Free fatty acid receptor 4, Anti-Omega-3 fatty acid receptor 1, Anti-Omega-3 fatty acid receptor 1, Anti-G-protein coupled receptor 120, Anti-G-protein coupled receptor 129, Anti-G-protein coupled receptor 120, Anti-G |
Supplier: | Cayman Chemical |
Supplier-Nr: | 15130 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic peptide from the N-terminal region of human FFAR4 (GPR120) |
MW: | 45 kD |
Format: | Solid |
Database Information
KEGG ID : | K08425 | Matching products |
UniProt ID : | Q5NUL3 | Matching products |
Gene ID : | GeneID 338557 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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