Anti-EPRS

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-957A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A303-957A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in... more

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Product information "Anti-EPRS"

Protein function: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (PubMed:1756734, PubMed:24100331, PubMed:23263184). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript- selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium]

Keywords:	Anti-EPRS, Anti-GLNS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Prolyl-tRNA synthetase, Anti-Glutamate--tRNA ligase, Anti-Glutamyl-tRNA synthetase, Anti-Glutamatyl-prolyl-tRNA synthetase
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-957A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon, thirteen-lined ground squirrel)
Immunogen:	synthetic peptide. The epitope recognized by A303-957A-T maps to a region between residue 150 to 200 of human Glutamyl-prolyl-tRNA Synthetase using the numbering given in entry NP_004437.2 (GeneID 2058).
Format:	Antigen Affinity Purified