Anti-EPHX2 / Epoxide hydrolase 2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32613 100 µg - -

3 - 10 business days*

772.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Soluble epoxide hydrolase (sEH), or... more
Product information "Anti-EPHX2 / Epoxide hydrolase 2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Soluble epoxide hydrolase (sEH), or Epoxide hydrolase 2, is a bifunctional enzyme that in humans is encoded by the EPHX2 gene. It is mapped to 8p21.2-p21.1. This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described. Protein function: Bifunctional enzyme (PubMed:12574510). The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides (PubMed:12869654, PubMed:12574510, PubMed:22798687). Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators (PubMed:12869654, PubMed:12574510, PubMed:22798687). The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy- octadec-9E-enoic acid (PubMed:12574510). [The UniProt Consortium]
Keywords: Anti-SEH, Anti-CEH, Anti-EPHX2, Anti-Epoxide hydratase, Anti-Soluble epoxide hydrolase, Anti-Lipid-phosphate phosphatase, Anti-Cytosolic epoxide hydrolase 2, Anti-Bifunctional epoxide hydrolase 2, EPHX2 Antibody / Epoxide hydrolase 2
Supplier: NSJ Bioreagents
Supplier-Nr: R32613

Properties

Application: WB, FC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Amino acids 505-543 (QHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLD-human)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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