Anti-Eosinophil Peroxidase, clone rEPO104

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V8515-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V8515-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Peripheral blood... more
Product information "Anti-Eosinophil Peroxidase, clone rEPO104"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Protein function: Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. [The UniProt Consortium]
Keywords: Anti-EPX, Anti-EPER, EC=1.11.1.7, Eosinophil Peroxidase Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V8515

Properties

Application: IHC (paraffin), FC, IF
Antibody Type: Monoclonal
Clone: rEPO104
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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