Anti-Eosinophil Peroxidase, clone AHE-1

Anti-Eosinophil Peroxidase, clone AHE-1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2302SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. Peripheral blood granulocytes are classified... more
Product information "Anti-Eosinophil Peroxidase, clone AHE-1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Protein function: Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. [The UniProt Consortium]
Keywords: Anti-EPX, Anti-EPER, EC=1.11.1.7, Eosinophil Peroxidase Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2302SAF

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: AHE-1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome were used as the immunogen for this Eosinophil peroxidase antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-Eosinophil Peroxidase, clone AHE-1"
Write a review
or to review a product.
Viewed