Anti-EEF1A1

This affinity purified antibody is directed against human EEF1A1.  This product is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above.  A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to EEF1A1 human, mouse, rat, bovine, rabbit, cat, horse, Chinese hamster, Gallus gallus, Pan troglodytes, and Pongo abelii. May have cross-reactivity to EEF1A to Danio rerio, and eef1as to Xenopus laevis. Protein function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. [The UniProt Consortium]