Anti-DUSP13, SKRP4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-11-8025-100	100 µg		-		3 - 11 business days*		387.00€

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DUSP13 is a member of the protein-tyrosine phosphatase superfamily which can act on both... more

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Product information "Anti-DUSP13, SKRP4"

DUSP13 is a member of the protein-tyrosine phosphatase superfamily which can act on both phosphotyrosine and phosphoserine/threonine residues. Two different but related isoforms are reported, viz., A and B. DUSP13 gene encodes different but related DSP proteins through the use of non-overlapping ORFs and alternate splicing. DUSP13A has been implicated in MAP3K5/ASK1-mediated apoptosis. The B isoform dephosphorylates MAPK8/JNK and MAPK14/p38. This protein has been implicated in postnatal development of specific tissues. Protein function: Probable protein tyrosine phosphatase. Has phosphatase activity with synthetic substrates (PubMed:15252030, PubMed:29106959). Has a phosphatase activity-independent regulatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1. [The UniProt Consortium]

Keywords:	Anti-BEDP, Anti-MDSP, Anti-DUSP13, Anti-DUSP13A, EC=3.1.3.16, Anti-Muscle-restricted DSP, Anti-Branching-enzyme interacting DSP, Anti-Dual specificity protein phosphatase 13 isoform A, Polyclonal Antibody to DUSP13, SKRP4
Supplier:	Abeomics
Supplier-Nr:	11-8025

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Full length recombinant DUSP13 protein was used as the immunogen for this antibody.
Format:	Purified