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![Anti-DR3 (Death Receptor 3)](https://www.biomol.com/media/image/27/4b/3f/NSJ-F45569-0-08ML_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F45569-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F45569-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a member of the... more
Product information "Anti-DR3 (Death Receptor 3)"
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. Protein function: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. [The UniProt Consortium]
Keywords: | Anti-APO3, Anti-LARD, Anti-Apo-3, Anti-TNFRSF25, Anti-Protein WSL, Anti-Protein WSL-1, Anti-Death receptor 3, Anti-Apoptosis-inducing receptor AIR, Anti-Apoptosis-mediating receptor DR3, Anti-Apoptosis-mediating receptor TRAMP, DR3 Antibody (Death Recepto |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F45569 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 214-242 from the human protein was used as the immunogen for this DR3 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05160 | Matching products |
UniProt ID : | Q93038 | Matching products |
Gene ID | GeneID 8718 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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