Anti-DNMT1, Internal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64495.100	100 µg		-	-	6 - 14 business days*		822.00€

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Protein function: Methylates CpG residues. Preferentially methylates hemimethylated DNA.... more

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Product information "Anti-DNMT1, Internal"

Protein function: Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. [The UniProt Consortium]

Keywords:	Anti-AIM, Anti-MCMT, Anti-DNMT1, Anti-Dnmt1, Anti-M.HsaI, EC=2.1.1.37, Anti-DNA MTase HsaI, Anti-DNA methyltransferase HsaI, Anti-CXXC-type zinc finger protein 9, Anti-DNA (cytosine-5)-methyltransferase 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64495

Properties

Application:	ELISA, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, canine, bovine, swine)
Immunogen:	C-RFESPPKTQPTEDN
Format:	Ammonium Sulfate Precipitated