Anti-Death Receptor 4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-982	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-DR4 Antibody is directed against human DR4 protein. The product was affinity purified from... more

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Product information "Anti-Death Receptor 4"

Anti-DR4 Antibody is directed against human DR4 protein. The product was affinity purified from monospecific antiserum. The antibody is human, mouse and rat reactive. Reactivity against homologues from other sources has not been determined. Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. [The UniProt Consortium]

Keywords:	Anti-APO2, Anti-CD261, Anti-TRAIL-R1, Anti-TNFRSF10A, Anti-TRAIL receptor 1, Anti-Death receptor 4, Anti-TNF-related apoptosis-inducing ligand receptor 1, Anti-Tumor necrosis factor receptor superfamily member 10A
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-982

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	peptide corresponding to amino acids near the c-terminus of human DR4 protein.
Format:	Purified