Anti-CYP2C8 (PACO02537)

Anti-CYP2C8 (PACO02537)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-PACO02537.50 50 µg - -

9 - 20 business days*

320.00€
 
CYP2C8 Antibody from Assay Genie with reactivity against Human and for use in ELISA, WB... more
Product information "Anti-CYP2C8 (PACO02537)"
CYP2C8 Antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. CYP2C8 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins (PubMed:7574697, PubMed:11093772, PubMed:14559847, PubMed:15766564, PubMed:19965576). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:7574697, PubMed:11093772, PubMed:14559847, PubMed:15766564, PubMed:19965576). Primarily catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA) with a preference for the last double bond (PubMed:7574697, PubMed:15766564, PubMed:19965576). Catalyzes the hydroxylation of carbon-hydrogen bonds. Metabolizes all trans-retinoic acid toward its 4-hydroxylated form (PubMed:11093772). Displays 16-alpha hydroxylase activity toward estrogen steroid hormones, 17beta-estradiol (E2) and estrone (E1) (PubMed:14559847). Plays a role in the oxidative metabolism of xenobiotics. It is the principal enzyme responsible for the metabolism of the anti-cancer drug paclitaxel (taxol) (PubMed:26427316). [The UniProt Consortium]
Keywords: Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-20, Anti-Cytochrome P450 MP-12, Anti-Cytochrome P450 form 1, Anti-S-mephenytoin 4-hydroxylase
Supplier: Assay Genie
Supplier-Nr: PACO02537

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: synthesized peptide derived from the Internal region of human CYP2C8.
Formula: affinity purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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