Anti-CYP11B1 + CYP11B2

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG66853.100	100 µg		-	-	6 - 14 business days*		30 %	584.00€ 408.80€

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Protein function: A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal... more

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Product information "Anti-CYP11B1 + CYP11B2"

Protein function: A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids (PubMed:18215163). Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11- deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively (PubMed:18215163). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron- sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PubMed:18215163). {ECO:0000269, PubMed:18215163}. [The UniProt Consortium]

Keywords:	Anti-S11BH, Anti-CYPXIB1, Anti-CYPXIB1, Anti-Cytochrome P450C11, Anti-Cytochrome P450C11, Anti-Cytochrome P-450c11, Anti-Cytochrome P-450c11, Anti-Cytochrome P450 11B1, mitochondrial, Anti-Cytochrome P450 11B1, mitochondrial, Anti-Steroid 11-beta-hydroxyl
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66853

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide derived from the C-terminal region of Human CYP11B1/2
MW:	58 kD
Format:	Antigen Affinity Purified