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![Anti-Cyclophilin A (Peptidyl-prolyl Cis-trans Isomerase A, PPIase A, Cyclosporin A-binding Protein,](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C8850-05A.100 | 100 µg | - | - |
3 - 19 business days* |
1,007.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cyclophilin A, also called Peptidylprolyl Isomerase A, PPIA, CYPA, and CYPH, was originally... more
Product information "Anti-Cyclophilin A (Peptidyl-prolyl Cis-trans Isomerase A, PPIase A, Cyclosporin A-binding Protein,"
Cyclophilin A, also called Peptidylprolyl Isomerase A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis-and trans-proline residues critical for proper folding of proteins. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity. Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.1ug/ml, Immunocytochemistry: 5-15ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-PPIA, Anti-CYPA, EC=5.2.1.8 |
Supplier: | United States Biological |
Supplier-Nr: | C8850-05A |
Properties
Application: | ICC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant corresponding to aa1-185 from human Cyclophilin A expressed in E.coli. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K03767 | Matching products |
UniProt ID : | P62937 | Matching products |
Gene ID | GeneID 5478 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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