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![Anti-Cyclin B2 Monoclonal Antibody (Clone: X29.2)](https://www.biomol.com/media/image/60/91/6e/ABE-36-3459-20_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-36-3459-20 | 20 µg | - |
3 - 11 business days* |
375.00€
|
|||
ABE-36-3459-100 | 100 µg | - |
3 - 11 business days* |
853.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known... more
Product information "Anti-Cyclin B2 Monoclonal Antibody (Clone: X29.2)"
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1). The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions. Protein function: Essential for the control of the cell cycle at the G2/M (mitosis) transition. [The UniProt Consortium]
Keywords: | Anti-CCNB2, Anti-G2/mitotic-specific cyclin-B2, Anti-Cyclin B2 Monoclonal Antibody (Clone: X29.2) |
Supplier: | Abeomics |
Supplier-Nr: | 36-3459 |
Properties
Application: | ELISA |
Antibody Type: | Monoclonal |
Clone: | X29.2 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | mouse, rat, human |
Immunogen: | Recombinant full-length Xenopus laevis Cyclin B2 protein |
Database Information
KEGG ID : | K21770 | Matching products |
UniProt ID : | O95067 | Matching products |
Gene ID | GeneID 9133 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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