Anti-CYB5R3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ6610 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NADH-cytochrome b5 reductase 3 is an... more
Product information "Anti-CYB5R3"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NADH-cytochrome b5 reductase 3 is an enzyme that in humans is encoded by the CYB5R3 gene. This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. Protein function: Transfers two electrons from NADH to two molecules of cytochrome b5 through an enzyme-bound FAD. Electrons from the reduced cytochrome b5 are then transferred to various electron acceptors, thereby participating in methemoglobin reduction in red blood cells and in the desaturation and elongation of fatty acids, cholesterol biosynthesis and cytochrome P-450-mediated drug metabolism other tissues. [The UniProt Consortium]
Keywords: Anti-DIA1, CYB5R3 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: RQ6610

Properties

Application: WB, IF, FC, Direct ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant human protein (amino acids M24-F301)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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