Anti-CYB5R3

Anti-CYB5R3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES2077.50 50 µl - -

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169.00€
ELK-ES2077.100 100 µl - -

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283.00€
 
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells... more
Product information "Anti-CYB5R3"
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010], Protein function: Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: [Isoform 1]: Endoplasmic reticulum membrane, Lipid-anchor, Cytoplasmic side. Mitochondrion outer membrane, Lipid-anchor, Cytoplasmic side., [Isoform 2]: Cytoplasm. Produces the soluble form found in erythrocytes.
Keywords: Anti-B5R, Anti-DIA1, Anti-Diaphorase-1, Anti-Cytochrome b5 reductase, Anti-NADH-cytochrome b5 reductase 3, CYB5R3 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES2077

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse,
Immunogen: The antiserum was produced against synthesized peptide derived from human CYB5R3. AA range:137-186
MW: 34 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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