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![Anti-CTLA-4 Monoclonal Antibody (Clone:IHC004)](https://www.biomol.com/media/image/2a/b6/9d/ABE-44-1023-0-1_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-44-1023-0.1 | 100 µl | - |
3 - 11 business days* |
620.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a receptor on T Helper cells that... more
Product information "Anti-CTLA-4 Monoclonal Antibody (Clone:IHC004)"
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a receptor on T Helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations in CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE), celiac disease, primary biliary cirrhosis, thyroid-associated orbitopathy, multiple sclerosis, and other autoimmune diseases. The spliced variant of CTLA-4 in SLE is present in the patient's serum. Haploinsufficiency of CTLA-4 causes the immune system disorder known as CTLA-4 deficiency or CHAI disease (CTLA4 haploinsufficiency with autoimmune infiltration). Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
Keywords: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen 4, Anti-CTLA-4 Monoclonal Antibody (Clone:IHC004) |
Supplier: | Abeomics |
Supplier-Nr: | 44-1023-0.1 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | IHC004 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant Human CTLA-4 |
Format: | Purified |
Database Information
KEGG ID : | K06538 | Matching products |
UniProt ID : | P16410 | Matching products |
Gene ID | GeneID 1493 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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