Anti-CP110

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-344A-T	10 µl (2 µg)		-		2 - 8 business days*		178.00€
A301-344A	100 µl		-		2 - 8 business days*		630.00€

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Protein function: Necessary for centrosome duplication at different stages of procentriole... more

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Product information "Anti-CP110"

Protein function: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [The UniProt Consortium]

Keywords:	Anti-CP110, Anti-Cep110, Anti-CEP110, Anti-CCP110, Anti-Centrosomal protein of 110 kDa, Anti-Centriolar coiled-coil protein of 110 kDa
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-344A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, african elephant, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-344A-T maps to a region between residue 962 and 1012 of human centrosomal protein 110kDa using the numbering given in entry CAH18111.1 (GeneID 9738).
Format:	Antigen Affinity Purified