Anti-CNDP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA036898.25	25 µl		-		7 - 10 business days*		239.00€
ATA-HPA036898.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong... more

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Product information "Anti-CNDP2"

Protein function: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 92%

Keywords:	Anti-CN2, Anti-CNDP2, Anti-Peptidase A, EC=3.4.13.18, Anti-CNDP dipeptidase 2, Anti-Carnosine dipeptidase II, Anti-Epididymis secretory protein Li 13, Anti-Cytosolic non-specific dipeptidase, Anti-Glutamate carboxypeptidase-like protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA036898

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AKWVAIQSVS AWPEKRGEIR RMMEVAAADV KQLGGSVELV DIGKQKLPDG SEIPLPPILL GRLGSDPQKK TVCI (ATA-APrEST87215)