Anti-CLPX

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59262.100	100 µl		-	-	6 - 14 business days*		616.00€

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Protein function: ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP... more

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Product information "Anti-CLPX"

Protein function: ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP (PubMed:28874591). Targets specific substrates for degradation by the Clp complex (PubMed:11923310, PubMed:22710082). Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure (PubMed:22841477). ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5- aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis (PubMed:28874591). Important for efficient erythropoiesis through upregulation of heme biosynthesis (PubMed:25957689, PubMed:28874591). [The UniProt Consortium]

Keywords:	Anti-CLPX, Anti-ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59262

Properties

Application:	FC, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rat)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 449-477 (C-terminus) of Human CLPX
MW:	69 kD
Format:	Purified