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![Anti-CFTR / Cystic Fibrosis Transmembrane Regulator, clone CFTR/1775R (recombinant antibody)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3441IHC-7ML | 7 ml | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-CFTR / Cystic Fibrosis Transmembrane Regulator, clone CFTR/1775R (recombinant antibody)"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Recognizes a protein of 165-170kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Protein function: Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [The UniProt Consortium]
Keywords: | Anti-CFTR, Anti-ABCC7, EC=3.6.3.49, Anti-cAMP-dependent chloride channel, Anti-Channel conductance-controlling ATPase, Anti-ATP-binding cassette sub-family C member 7, Anti-Cystic fibrosis transmembrane conductance regulator, Recombinant CFTR Antibody / C |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3441IHC |
Properties
Application: | IF, IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | CFTR/1775R |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A recombinant partial protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this recombinant CFTR antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05031 | Matching products |
UniProt ID : | P13569 | Matching products |
Gene ID | GeneID 1080 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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