Anti-CFD / Complement Factor D

Anti-CFD / Complement Factor D
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ4074 100 µg - -

3 - 10 business days*

772.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Factor D is a protein which in humans is... more
Product information "Anti-CFD / Complement Factor D"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Factor D is a protein which in humans is encoded by the CFD gene. The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. And it stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. Protein function: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. [The UniProt Consortium]
Keywords: Anti-Cfd, Anti-Adn, Anti-Adipsin, EC=3.4.21.46, Anti-Properdin factor D, Anti-Complement factor D, Anti-C3 convertase activator, Anti-Endogenous vascular elastase, CFD Antibody / Complement Factor D
Supplier: NSJ Bioreagents
Supplier-Nr: RQ4074

Properties

Application: WB, IHC (paraffin), ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse, rat
Immunogen: A recombinant rat partial protein corresponding to amino acids I26-A263 was used as the immunogen for the Factor D antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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