Anti-CERS6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA063527.25	25 µl		-		7 - 10 business days*		239.00€
ATA-HPA063527.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Ceramide synthase that catalyzes formation of ceramide from sphinganine and... more

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Product information "Anti-CERS6"

Protein function: Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA, C16:0-CoA) as acyl donor (PubMed:17977534, PubMed:17609214, PubMed:23530041, PubMed:26887952, PubMed:31916624). Can use other acyl donors, but with less efficiency. Ceramides generated by CERS6 play a role in inflammatory response. Acts as a regulator of metabolism and hepatic lipid accumulation. Under high fat diet, palmitoyl- (C16:0-) ceramides generated by CERS6 specifically bind the mitochondrial fission factor MFF, thereby promoting mitochondrial fragmentation and contributing to the development of obesity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-CerS6, Anti-Ceramide synthase 6, Anti-LAG1 longevity assurance homolog 6
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA063527

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: WLPHNVTWAD LKNTEEATFP QAEDL (ATA-APrEST92356)