Anti-CDC42BPA

Anti-CDC42BPA
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB18396.20 20 µl - -

9 - 20 business days*

138.00€
G-CAB18396.100 100 µl -

9 - 20 business days*

384.00€
 
Protein function: Serine/threonine-protein kinase which is an important downstream effector of... more
Product information "Anti-CDC42BPA"
Protein function: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration (PubMed:15723050, PubMed:9092543, PubMed:9418861). Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates: PPP1R12A, LIMK1 and LIMK2 (PubMed:11340065, PubMed:11399775). May play a role in TFRC-mediated iron uptake (PubMed:20188707). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. Triggers the formation of an extrusion apical actin ring required for epithelial extrusion of apoptotic cells (PubMed:29162624). [The UniProt Consortium]
Keywords: Anti-KIAA0451, Anti-MRCK alpha, Anti-DMPK-like alpha, Anti-CDC42-binding protein kinase alpha, Anti-Serine/threonine-protein kinase MRCK alpha, Anti-Myotonic dystrophy protein kinase-like alpha, CDC42BPA Polyclonal Antibody
Supplier: Assay Genie
Supplier-Nr: CAB18396

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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