Anti-CD85j / LIR-1, clone 4F9

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Save 30% on all primary antibodies by Arigo Biolaboratories!

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG23623.100	100 µg		-	-	6 - 14 business days*		30 %	624.00€ 436.80€

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Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B,... more

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Product information "Anti-CD85j / LIR-1, clone 4F9"

Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. [The UniProt Consortium]

Keywords:	Anti-ILT2, Anti-CD85j, Anti-ILT-2, Anti-MIR-7, Anti-LIR-1, Anti-LILRB1, Anti-Immunoglobulin-like transcript 2, Anti-CD85 antigen-like family member J, Anti-Leukocyte immunoglobulin-like receptor 1, Anti-Monocyte/macrophage immunoglobulin-like receptor 7
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG23623

Properties

Application:	IHC (frozen), FC
Antibody Type:	Monoclonal
Clone:	4F9
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Monocyte derived dendritic cells
Format:	Purified