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![Anti-CD80 (CD80 Antigen, CD80 Molecule, Activation B7-1 Antigen, B-lymphocyte Activation Antigen B7,](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2432-01R.100 | 100 µg | - | - |
3 - 19 business days* |
591.00€
|
||
C2432-01R.200 | 200 µg | - | - |
3 - 19 business days* |
803.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD80 is a member of the immunoglobulin superfamily having an extracellular domain bearing both a... more
Product information "Anti-CD80 (CD80 Antigen, CD80 Molecule, Activation B7-1 Antigen, B-lymphocyte Activation Antigen B7,"
CD80 is a member of the immunoglobulin superfamily having an extracellular domain bearing both a single Ig-v-like domain, a single Ig-c-like domain, a transmembrane sequence and a short cytoplasmic domain. Although the predicted molecular weight for human CD80 is ~33kD, the presence of multiple (8) potential N-glycosylation sites results in a migration corresponding to ~60kD. Human CD80 along with CD86 act as co-stimulatory molecules and are both ligands for CD28 and CTLA-4 involved in T cell activation and proliferation. Although CD80 binds to the same receptors as CD86 it displays quite different characteristics in its avidity and binding kinetics. CD80 is expressed by activated B cells, and is important in B cell-T cell interactions, being a ligand of CD28 and CD152 (CTLA-4). CD80, also known as B7-1, a ~60kD type 1 trans-membrane protein expressed of macrophages, dendritic cells and activated B-cells. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Western Blot. Other applications have not been tested. Recommended Dilution: Flow Cytometry: 10ul labels 10e6 cells or 100ul whole blood, Western Blot: Non-reducing conditions, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-B7, Anti-BB1, Anti-CD80, Anti-CD28LG, Anti-Activation B7-1 antigen, Anti-CTLA-4 counter-receptor B7.1, Anti-T-lymphocyte activation antigen CD80 |
Supplier: | United States Biological |
Supplier-Nr: | C2432-01R |
Properties
Application: | FC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | 3H1689 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human CD80. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K05412 | Matching products |
UniProt ID : | P33681 | Matching products |
Gene ID | GeneID 941 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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