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![Anti-CD80 (B7-1 Costimulator Protein), Biotin conjugated, clone 5K18](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2432-14B.500 | 500 µg | - | - |
3 - 19 business days* |
508.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily... more
Product information "Anti-CD80 (B7-1 Costimulator Protein), Biotin conjugated, clone 5K18"
CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours postactivation. 1-4 The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. This antibody locks binding of CTLA-4 to CD80, but it does not block stimulation of T cells by natural antigen presenting cells. 2, 7, Applications: Flow cytometry 2, 7, Immunoprecipitation 7, In vivo and in vitro blocking of ligand binding 7, Recommended Dilution: Flow Cytometry: < 1ug/10e6 cells, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-B7, Anti-CD80, Anti-Cd80, Anti-Activation B7-1 antigen, Anti-T-lymphocyte activation antigen CD80 |
Supplier: | United States Biological |
Supplier-Nr: | C2432-14B |
Properties
Application: | FC, IP |
Antibody Type: | Monoclonal |
Clone: | 5K18 |
Conjugate: | Biotin |
Host: | Rat |
Species reactivity: | mouse |
Format: | Purified |
Database Information
KEGG ID : | K05412 | Matching products |
UniProt ID : | Q00609 | Matching products |
Gene ID | GeneID 12519 | Matching products |
Handling & Safety
Storage: | -20°C (frozen cool packs!) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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