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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1936-100 | 100 tests | - |
3 - 11 business days* |
714.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK... more
Product information "Anti-CD7 (Clone: MEM-186), FITC conjugated"
CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics. Protein function: Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors (PubMed:7506726). Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1 (PubMed:10652336). In turn, mediates the production of cytokines such as IL-2 (PubMed:1709867). On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels (PubMed:7506726). [The UniProt Consortium]
Keywords: | Anti-CD7, Anti-TP41, Anti-GP40, Anti-T-cell antigen CD7, Anti-T-cell leukemia antigen, Anti-T-cell surface antigen Leu-9, Anti-CD7 Monoclonal Antibody (Clone:MEM-186)-FITC Conjugated |
Supplier: | Abeomics |
Supplier-Nr: | 30-1936 |
Properties
Application: | FC, IP, WB, IHC |
Antibody Type: | Monoclonal |
Clone: | MEM-186 |
Conjugate: | Fluorescein |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human acute myelogenous leukaemia cell line KG-1. |
Database Information
KEGG ID : | K06457 | Matching products |
UniProt ID : | P09564 | Matching products |
Gene ID : | GeneID 924 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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