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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1167-0.1 | 100 µg | - |
3 - 11 business days* |
580.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by... more
Product information "Anti-CD50 / ICAM-3 Monoclonal Antibody (Clone:MEM-171)"
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages, this process is involved in dialogue between dendritic cells and granulocytes. Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). [The UniProt Consortium]
Keywords: | Anti-CD50, Anti-ICAM3, Anti-CDw50, Anti-ICAM-3, Anti-ICAM-R, Anti-Intercellular adhesion molecule 3, Anti-CD50 / ICAM-3 Monoclonal Antibody (Clone:MEM-171) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1167 |
Properties
Application: | FC, IP |
Antibody Type: | Monoclonal |
Clone: | MEM-171 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human granulocytes |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06486 | Matching products |
UniProt ID : | P32942 | Matching products |
Gene ID : | GeneID 3385 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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