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Product information "Anti-CD46 antibody(DM145), Rabbit mAb"
Protein function: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. [The UniProt Consortium]
Keywords:
Anti-CD46, Anti-AHUS2, Anti-MCP, Anti-MIC10, Anti-TLX, Anti-TRA2.10, Anti-CD46 antibody(DM145), Rabbit mAb
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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