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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1017-0.1 | 100 µg | - |
3 - 11 business days* |
594.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell... more
Product information "Anti-CD40 Monoclonal Antibody (Clone:HI40a)-Azide free"
CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types, such as B cells, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules. Protein function: Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
Keywords: | Anti-Bp50, Anti-CD40, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L receptor, Anti-B-cell surface antigen CD40, Anti-Tumor necrosis factor receptor superfamily member 5, Anti-CD40 Monoclonal Antibody (Clone:HI40a)-Azide free |
Supplier: | Abeomics |
Supplier-Nr: | 30-1017 |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | HI40a |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human CD40a |
Format: | Affinity Purified |
Database Information
KEGG ID : | K03160 | Matching products |
UniProt ID : | P25942 | Matching products |
Gene ID : | GeneID 958 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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