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![Anti-CD40, clone T8P2G4*A6](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3792SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. This antibody is specific for the soluble form of... more
Product information "Anti-CD40, clone T8P2G4*A6"
1 mg/ml in 1X PBS, BSA free, sodium azide free. This antibody is specific for the soluble form of CD40.áIt is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is expressed on B-lymphocytes, follicular dendritic cells, bone marrow-derived dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zones of secondary lymphoid organs. Protein function: Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
Keywords: | Anti-CD40, Anti-Bp50, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L receptor, Anti-B-cell surface antigen CD40, Anti-Tumor necrosis factor receptor superfamily member 5, CD40 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3792SAF |
Properties
Application: | FC, IF |
Antibody Type: | Monoclonal |
Clone: | T8P2G4*A6 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | C-terminal region amino acids RDPVCHPLGA |
Format: | Purified |
Database Information
KEGG ID : | K03160 | Matching products |
UniProt ID : | P25942 | Matching products |
Gene ID | GeneID 958 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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