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Track device being used
![Anti-CD3E (human), Rabbit Monoclonal (RM344)](https://www.biomol.com/media/image/7e/bd/18/REV-31-1229-00-R100_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
REV-31-1229-00-R100 | 100 µl | - | - |
3 - 9 business days* |
483.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Recombinant Antibody. This antibody reacts to the cytoplasmic domain of human CD3 epsilon chain.... more
Product information "Anti-CD3E (human), Rabbit Monoclonal (RM344)"
Recombinant Antibody. This antibody reacts to the cytoplasmic domain of human CD3 epsilon chain. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The CD3 subunit complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum, but it is not expressed on B or NK cells. T-cell surface glycoprotein CD3 epsilon chain has been shown to interact with TOP2B, CD3EAP and NCK2.
Keywords: | T-cell Surface Glycoprotein CD3 epsilon Chain |
Supplier: | RevMAb Biosciences |
Supplier-Nr: | 31-1229-00 |
Properties
Application: | WB, IHC |
Antibody Type: | Monoclonal |
Clone: | RM344 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K06451 | Matching products |
UniProt ID : | P07766 | Matching products |
Gene ID | GeneID 916 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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