Anti-CD3e, clone PC3/188A

Anti-CD3e, clone PC3/188A
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3462-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V3462-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Recognizes the... more
Product information "Anti-CD3e, clone PC3/188A"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Recognizes the epsilon chain of CD3, a protein which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. Protein function: The CD3 complex mediates signal transduction, resulting in T-cell activation and proliferation. Required for normal immune responses (PubMed:15546002, PubMed:8490660). [The UniProt Consortium]
Keywords: Anti-T3E, Anti-CD3e, Anti-CD3E, Anti-T-cell surface glycoprotein CD3 epsilon chain, Anti-T-cell surface antigen T3/Leu-4 epsilon chain, CD3e Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3462

Properties

Application: WB, IHC (paraffin), FC, IF
Antibody Type: Monoclonal
Clone: PC3/188A
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, rat, rabbit, guinea pig, swine, horse, bovine
Immunogen: Amino acids 156-168 (cytoplasmic domain) from human CD3 epsilon chain were used as the immunogen for the CD3e antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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