Anti-CD262, clone DR5-01-1 (FITC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG53806.50	50 µg		-	-	6 - 14 business days*		456.00€

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Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD... more

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Product information "Anti-CD262, clone DR5-01-1 (FITC)"

Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis. [The UniProt Consortium]

Keywords:	Anti-DR5, Anti-CD262, Anti-TRAIL-R2, Anti-TNFRSF10B, Anti-Death receptor 5, Anti-TRAIL receptor 2, Anti-TNF-related apoptosis-inducing ligand receptor 2, Anti-Tumor necrosis factor receptor superfamily member 10B
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG53806

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	DR5-01-1
Conjugate:	FITC
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant fusion protein of human IgG heavy chain and extracellular domain of DR5
Format:	Liquid