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![Anti-CD22, Phycoerythrin conjugated, clone 2Q1605](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2272-88D.100 | 100 µg | - | - |
3 - 19 business days* |
438.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a... more
Product information "Anti-CD22, Phycoerythrin conjugated, clone 2Q1605"
CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor crosslinking and is involved in negative regulation of B-cell activation. Applications: Flow cytometry 2, Blocking of B cell homotypic adhesion 2, Recommended Dilution: Flow Cytometry: < 0.2ug/10e6 cells, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-CD22, Anti-Cd22, Anti-Lyb-8, Anti-BL-CAM, Anti-Siglec-2, Anti-B-cell receptor CD22, Anti-T-cell surface antigen Leu-14, Anti-B-lymphocyte cell adhesion molecule, Anti-Sialic acid-binding Ig-like lectin 2 |
Supplier: | United States Biological |
Supplier-Nr: | C2272-88D |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 5K249 |
Conjugate: | Phycoerythrin |
Host: | Rat |
Species reactivity: | mouse |
Format: | Purified |
Database Information
KEGG ID : | K06467 | Matching products |
UniProt ID : | P35329 | Matching products |
Gene ID | GeneID 12483 | Matching products |
Handling & Safety
Storage: | -20°C (frozen cool packs!) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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