Anti-CD22

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA066523.100	100 µl				7 - 10 business days*		450.00€

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Polyclonal Antibody against Human CD22, Gene description: CD22 molecule, Alternative Gene Names:... more

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Product information "Anti-CD22"

Polyclonal Antibody against Human CD22, Gene description: CD22 molecule, Alternative Gene Names: SIGLEC-2, SIGLEC2, Validated applications: IHC, Uniprot ID: P20273, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. [The UniProt Consortium] Mouse gene identity: 56% Rat gene identity: 56%

Keywords:	Anti-CD22, Anti-BL-CAM, Anti-SIGLEC2, Anti-Siglec-2, Anti-B-cell receptor CD22, Anti-T-cell surface antigen Leu-14, Anti-B-lymphocyte cell adhesion molecule, Anti-Sialic acid-binding Ig-like lectin 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA066523

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (ATA-APrEST95704)
Format:	Affinity Purified