Anti-CD200R1 (Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor,

CD200 R1, also known as OX-2 receptor, is one of four CD200 R-related proteins within the immunoglobulin superfamily. CD200 R1 is a type I transmembrane protein with a PTB-signaling motif in its cytoplasmic domain. Engagement of CD200 R1 by CD200 elicits an inhibitory signal in mast cells, basophils, macrophages, and dendritic cells. Alternate splicing of the human CD200 R1 mRNA generates four isoforms, two of which are truncated in the Ig-C2 domain and are likely secreted. Within the ECD, human CD200 R1 shares 56% aa sequence identity with mouse and rat CD200 R1. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Hybridoma: Myeloma with B cells from Balb/c mice. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.