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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine... more
Product information "Anti-CD192"
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. Protein function: Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426). Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). Transduces a signal by increasing intracellular calcium ion levels. Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable). [The UniProt Consortium]
Keywords: | Anti-CCR2, Anti-CD192, Anti-CCR-2, Anti-CMKBR2, Anti-MCP-1-R, Anti-CC-CKR-2, Anti-C-C CKR-2, Anti-C-C chemokine receptor type 2, Anti-Monocyte chemoattractant protein 1 receptor, CD192 Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-70194 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CCR2 |
Database Information
KEGG ID : | K04177 | Matching products |
UniProt ID : | P41597 | Matching products |
Gene ID | GeneID 729230 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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