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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2548-88K.100 | 100 µg | - | - |
3 - 19 business days* |
962.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD160 (also BY55) is a 27kD member of Ig Superfamily of molecules. It is expressed on select... more
Product information "Anti-CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28)"
CD160 (also BY55) is a 27kD member of Ig Superfamily of molecules. It is expressed on select hematopoietic cell types, including CD56dim CD16+cytotoxic NK cells, CD8+ CD28effector, T cells, gd T cells, and restricted CD4+ T cells. It is a receptor for HLAC molecules, and its engagement induces CD160+ NK cells to both secrete IFNg plus TNFg and initiate a cytotoxic program. Human CD160 was originally identified as a 155aa proprotein (aa27181). It contains a 132aa mature region (aa27159) and a Cterminal prosegment that is cleaved to create a GPI linkage. The mature region possesses one Vtype Ig like domain (aa27122). CD160 is found as a soluble, disulfidelinked 80kD multimer (likely trimer) that is generated by proteolysis of the, GPIlinked form. This 80kD form, plus others, are highly resistant to reduction. There is also a 100110kD multimeric transmembrane (TM) form that is associated with activated NK cells. It contains a 55aa substitution for Gly180Leu181, and shows a 20aa TM segment between aa 163182. The TM form appears to have a splice variant that lacks aa25133. Over aa27159,, human CD160 shares only 62% aa sequence identity with mouse CD160. Human CD160. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-CD160 antigen, Anti-Natural killer cell receptor BY55 |
Supplier: | United States Biological |
Supplier-Nr: | C2548-88K |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Sheep |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to Chinese hamster ovary cell line human CD160 expressed in CHO cells (O95971). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06542 | Matching products |
UniProt ID : | O95971 | Matching products |
Gene ID : | GeneID 11126 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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