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![Anti-CD16, clone HuNK2](https://www.biomol.com/media/image/7c/93/6d/NSJ-V2499-20UG_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V2499-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V2499-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 50-65kDa,... more
Product information "Anti-CD16, clone HuNK2"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 50-65kDa, identified as CD16 (Workshop IV, Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This mAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils. Protein function: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. [The UniProt Consortium]
Keywords: | Anti-CD16A, Anti-CD16a, Anti-FCGR3A, Anti-FcR-10, Anti-FcRIII, Anti-FcRIIIa, Anti-Fc-gamma RIII, Anti-CD16a antigen, Anti-Fc-gamma RIIIa, Anti-Fc-gamma RIII-alpha, Anti-IgG Fc receptor III-2, Anti-Low affinity immunoglobulin gamma Fc region receptor III-A |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V2499 |
Properties
Application: | FA (activity), FC, IF |
Antibody Type: | Monoclonal |
Clone: | HuNK2 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human peripheral blood lymphocytes from a NK-leukemia patient. |
Format: | Purified |
Database Information
KEGG ID : | K06463 | Matching products |
UniProt ID : | P08637 | Matching products |
Gene ID | GeneID 2214 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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