Anti-CD135 / FLT3

Anti-CD135 / FLT3
Anti-CD135 / FLT3
Anti-CD135 / FLT3
Anti-CD135 / FLT3
Anti-CD135 / FLT3
Anti-CD135 / FLT3
%
Discount Promotion
Promotion:

Save 30% on all primary antibodies by Arigo Biolaboratories!

*1
*1 Offer expires 16/12/2024
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
ARG43120.50 50 µg - -

6 - 14 business days*

30 %
520.00€
364.00€
 
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine... more
Product information "Anti-CD135 / FLT3"
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways. [The UniProt Consortium]
Keywords: Anti-Flt3, Anti-Flk-2, Anti-FLK-2, Anti-FLT-3, Anti-CD135, Anti-FLK-2, Anti-FLT-3, Anti-CD135, Anti-FL cytokine receptor, Anti-Fetal liver kinase 2, Anti-FL cytokine receptor, Anti-Fetal liver kinase 2, Anti-Fms-like tyrosine kinase 3, Anti-Fms-like tyros
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG43120

Properties

Application: IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse, rat
Immunogen: Recombinant protein corresponding to E62-E295 of Mouse CD135 / FLT3
MW: 113 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-CD135 / FLT3"
Write a review
or to review a product.
Viewed