Anti-CD11c Monoclonal Antibody (Clone:BU15)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-30-1367-0.1	100 µg		-		3 - 11 business days*		593.00€

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CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is... more

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Product information "Anti-CD11c Monoclonal Antibody (Clone:BU15)"

CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b. Protein function: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [The UniProt Consortium]

Keywords:	Anti-CD11c, Anti-ITGAX, Anti-CD11C, Anti-Leu M5, Anti-Integrin alpha-X, Anti-CD11 antigen-like family member C, Anti-Leukocyte adhesion receptor p150,95, Anti-Leukocyte adhesion glycoprotein p150,95 alpha chain, Anti-CD11c Monoclonal Antibody (Clone:BU15)
Supplier:	Abeomics
Supplier-Nr:	30-1367

Properties

Application:	FC, IP, IHC (frozen)
Antibody Type:	Monoclonal
Clone:	BU15
Conjugate:	No
Host:	Mouse
Species reactivity:	human, monkey
Immunogen:	Dendritic cells of synovial fluid
Format:	Affinity Purified