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![Anti-CAV1.2, clone S57-46](https://www.biomol.com/media/image/ce/77/d3/200-301-F08_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
200-301-F08 | 100 µg | - | - |
6 - 10 business days* |
698.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-CAV1.2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to... more
Product information "Anti-CAV1.2, clone S57-46"
Anti-CAV1.2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CAV1.2 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with CAV1.2 from other sources has not been determined. Channels and Transporters research. Protein function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin- GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1C subunit play an important role in excitation-contraction coupling in the heart. Binding of calmodulin or CABP1 at the same regulatory sites results in an opposit effects on the channel function. [The UniProt Consortium]
Keywords: | Anti-CACH2, Anti-CACNA1C, Anti-CACB-receptor, Anti-Smooth muscle calcium channel blocker receptor, Anti-Voltage-gated calcium channel subunit alpha Cav1.2, Anti-Voltage-dependent L-type calcium channel subunit alpha-1C, Anti-Calcium channel, L type |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 200-301-F08 |
Properties
Application: | IHC, IFM, IP, WB |
Antibody Type: | Monoclonal |
Clone: | S57-46 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
Immunogen: | fusion protein (intracellular carboxyl terminus) of rabbit Cav1.2. |
Format: | Purified |
Database Information
KEGG ID : | K04850 | Matching products |
UniProt ID : | P15381 | Matching products |
Gene ID | GeneID 100101555 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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