Anti-Caspase-9, clone 3B6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
E-AN007230L.25	25 µl		-		7 - 16 business days*		109.00€
E-AN007230L.100	100 µl		-		7 - 16 business days*		316.00€

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Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of... more

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Product information "Anti-Caspase-9, clone 3B6"

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage- induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC (PubMed:36758105, PubMed:36758106). [The UniProt Consortium]

Keywords:	Anti-MCH6, Anti-CASP9, Caspase-9 Monoclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AN007230L

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	3B6
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant Human Caspase-9 protein expressed by E.coli