Anti-Caspase-4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R30563	100 µg		-	-	3 - 10 business days*		755.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-4 is an enzyme that... more

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Product information "Anti-Caspase-4"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. The CASP4 gene is mapped to a P1 clone containing the ICE gene, which is located at chromosome 11q22.2-q22.3. It contains 8 coding exons. The function of Caspase-4 is not fully known, but it is believed to be an inflammatory caspase, along with CASP1, CASP5 and the murine homolog CASP11, with a role in the immune system. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1. [The UniProt Consortium]

Keywords:	Anti-ICH2, Anti-CASP4, EC=3.4.22.57, Caspase-4 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R30563

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Amino acids 104-124 (DALKLCPHEEFLRLCKERAEE-human) were used as the immunogen for this Caspase-4 antibody. This sequence is from the large subunit.
Format:	Purified