Anti-Caspase 3

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG67132.100	100 µl		-	-	6 - 14 business days*		30 %	584.00€ 408.80€

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Protein function: Involved in the activation cascade of caspases responsible for apoptosis... more

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Product information "Anti-Caspase 3"

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-, -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. {ECO:0000269, PubMed:21357690, ECO:0000269, PubMed:7596430}. [The UniProt Consortium]

Keywords:	Anti-CASP3, Anti-CPP32, Anti-SCA-1, Anti-CASP-3, Anti-CPP-32, Anti-Apopain, Anti-Caspase-3, Anti-Protein Yama, Anti-Caspase-3 subunit p17, Anti-Caspase-3 subunit p12, Anti-Cysteine protease CPP32, Anti-SREBP cleavage activity 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG67132

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide of Human Caspase 3
MW:	32 kD
Format:	Affinity Purified