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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F41865-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F41865-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. Caspases are cysteine proteases that cleave... more
Product information "Anti-Caspase-12"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. Protein function: Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF. [The UniProt Consortium]
Keywords: | Anti-CASP12, Anti-CASP-12, Anti-Inactive caspase-12, Caspase-12 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F41865 |
Properties
Application: | WB, IHC, FC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 165-193 from the human protein was used as the immunogen for this Caspase-12 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K04741 | Matching products |
UniProt ID : | Q6UXS9 | Matching products |
Gene ID : | GeneID 100506742 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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