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![Anti-Caspase 12 (CASP12, Caspase-12, CASP-12)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2088-59H.50 | 50 µg | - | - |
3 - 19 business days* |
789.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell... more
Product information "Anti-Caspase 12 (CASP12, Caspase-12, CASP-12)"
Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell death pathway. Caspase 12 is involved in the apoptosis triggered by a stress on the endoplasmic reticulum. Caspase-12 is colocalized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase 12 activation results in cell death in the absence of the cytochrome c-dependent pathway. Recently caspase-12 has been suggested to affect signaling pathways linking some G-protein coupled receptors to alphaIIbbeta3 activation. Caspase-12 is ubiquitously expressed in mouse tissues. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | C2088-59H |
Properties
Application: | IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse |
Immunogen: | Synthetic peptide corresponding to aa2-17 of mouse CASP12 (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04741 | Matching products |
UniProt ID : | O08736 | Matching products |
Gene ID | GeneID 12364 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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