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![Anti-Caspase-11 (mouse), clone 4E11](https://www.biomol.com/media/image/e5/35/a4/AG-20T-0140-C100_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-20T-0140-C100 | 100 µg | - |
3 - 9 business days* |
358.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory... more
Product information "Anti-Caspase-11 (mouse), clone 4E11"
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
Keywords: | Anti-Casp4, Anti-Casp11, EC=3.4.22.64 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-20T-0140 |
Properties
Application: | ELISA, FC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | 4E11 |
Conjugate: | No |
Host: | Rat |
Species reactivity: | mouse, rat |
Immunogen: | Recombinant mouse caspase-11 (p20 fragment) |
Purity: | >95% |
Format: | Purified |
Database Information
KEGG ID : | K04394 | Matching products |
UniProt ID : | P70343 | Matching products |
Gene ID | GeneID 12363 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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